The grant, totalling almost £3.7 million, has been awarded to Dr Sarah Harris of Lothian Birth Cohorts (LBC) to facilitate research into biomarkers for neurocognitive decline prior to dementia onset. The research project is a collaboration with The University of Texas at Austin, The University of Colorado at Boulder and The US National Institute on Aging.The aim is to identify blood-based protein biomarkers for the cognitive and structural brain changes that occur during the early stages of dementia before a clinical diagnosis of Alzheimer’s disease or other dementia-related disease.The project will measure up to 11,000 proteins in the Lothian Birth Cohort 1936 (LBC1936), one of the best-characterised longitudinal studies in the world, in blood plasma samples collected at ages 73, 76, 82 and 86 years. LBC1936 data will be combined with other world-class prospective studies of cognitive and brain aging, and dementia to create the largest study of protein biomarkers and longitudinal cognitive and brain changes to date. I was delighted to be awarded this grant. I truly hope that the results from this study will eventually lead to improved diagnosis of, and treatment for dementia. Dr Sarah Harris Senior Research Fellow, Lothian Birth Cohorts The funding has come from the US National Institutes of Health. Related links Lothian Birth Cohorts National Institutes of HealthCohort Profile Update: The Lothian Birth Cohorts of 1921 and 1936 Tags 2024 Publication date 11 Dec, 2024
